It may end up that over time we will find that the Four or Five Franco lineages are all part of one Franco family but today no one knows how they are all related. There are the descendents of Crispín Franco from
Today there are Franco's who trace back to Coyame, which is not far from Meoqui. Perhaps they are related. The Coyame Franco's are descendent's of Crispín Franco and have a strong presence in Pecos, Texas and have had family reunions in Colorado City, Texas.
The descendents of Francisco franco have an oral tradition that the Franco's came from Spain in 1802 and settled shortly after that in San Pablo, Meoqui, Chihuahua, Mexico. There are some family members who remember a photo of Franciscio in military attire with "El Coronel Franco" written on the photo. He may have been in the Mexican army. Maybe being in the military was a family tradition.
There are records of many Franco's in Meoqui in the 1800's. This makes it seem likely that Francisco Franco may have been related to the Antonio Franco Lineage. Since, Coyame is not very far from Meoqui on the way to Ojinaga and Presidio, It would not seem far fetched to consider that Crispín Franco is related to the Meoqui Franco's.